Impaired Fibrinolysis in Angiographically Documented Coronary Artery Disease

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Impaired Fibrinolysis in Angiographically Documented Coronary Artery Disease

Impaired fibrinolysis may predispose to coronary artery disease (CAD). Hypofibrinolysis due to high levels of plasminogen activator inhibitor-1 (PAI-1) has been reported in CAD. A novel regulator of fibrinolytic activity, thrombin activatable fibrinolysis inhibitor (TAFI), has attracted attention in recent years. It acts by blocking the formation of a ternary complex of plasminogen, fibrin, and...

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ژورنال

عنوان ژورنال: Advances in Hematology

سال: 2015

ISSN: 1687-9104,1687-9112

DOI: 10.1155/2015/214680